There is no preference on which method you use, instead, try to find what works best for your schedule and stick to it. Inactivity. For most women, 3-5 milligrams is a safe dose of DIM; higher doses may cause unwanted side effects. Before using DIM, anyone with liver or renal illness should talk to their doctor. Altering those levels by taking DIM is dangerous for you both. But since it has other effects as well, it is best used along with other methods of birth control. Avoid high glycemic foods such as refined sugar. Diindolylmethane. Hi Im a 21 year old male, I started taking progesterone in September of this year as a supplement to my trt regime (cancer survivor under doctor supervision). Progesterone also stabilizes the HPA (adrenal) axis and supports thyroid function. Don'ts Symptoms of detoxification should only last three to seven days. Then it began heavy with clotting, but not as bad as it usually is. Try diuretics. Memorial Sloan Kettering Cancer Center. In place of supplements, include cruciferous vegetables in your diet. Read More Which Type Of Supplement Will The Dietician Most Likely Recommend?Continue, Read More Where To Buy T-Drive Supplement?Continue, Read More What Is The Number One Food Supplement In The World?Continue, Read More What Is The Best Lactation Supplement?Continue, Read More What Does Pump Supplement Do?Continue, Read More Which Supplement Has Been Shown To Repair Connective Tissue?Continue, 2023 Health Articl - WordPress Theme by Kadence WP. Here's how it all goes down: You have 2 ovaries, and each one holds a bunch of eggs. This article reviews 10 actions you can take to help your hormones function optimally. Your hormones underlie many basic processes in your body. Research shows that about one in three cancer deaths is related to poor nutrition and could be prevented. I have my fingers crossed that it will be even slightly lighter than it has been. My May period came on day 23 (not great but more the norm for me) and my breasts were not as sore. Chewing cruciferous vegetables like broccoli, plant enzymes release DIM into your system. Dry skin is one sign of low estrogen. What does the thyroid have to do with estrogen? Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. In human research, doses typically range from 108900 mg per day though these studies were only related to treatments for cancer and prostate enlargement (8, 9, 14). It was not a great period but definitely better! The results will depend on your body, your diet, and your hormones. However, in a 6-month study in 551 women with cervical abnormalities, taking 150 mg of DIM per day had no effect on cervical cell changes (3, 13). For fertility: begin taking the herb regularly (daily) three months before you'd like to conceive. Being overweight might also have an impact on your menstrual period. Thats because DIM supports healthy estrogen levels in the body. This is why drinking ample water, eating fiber, supporting microbiome health, and ensuring regular bowel movements is so important to your hormone health. Also, it is asked, How quickly does DIM work? It may do so in several ways. They can also help you figure out what amount is right for your needs. Taking higher dosages of diindolylmethane might be dangerous. All About Natural and Pharmaceutical Estrogen Blockers for Males, Our Favorite Healthy Finds: Organic Beauty Products for Acne-Prone Skin, The 12 Best Collagen Supplements for Better Skin. Taking the pills with a meal may help with absorption and increase the supplement's benefits. A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen. For others, periods become significantly lighter. We know an imbalance of estrogen and progesterone is not ideal at any time, but during the perimenopausal period, it often dramatically affects a womans quality of life. Such individuals should steer clear of DIM supplements unless under the supervision of a medical professional. Starting with a lower dose of 50-100 mg is often best to avoid headaches, which can occur when you begin supplementing with DIM. Though DIM supplements are popular, there is still no significant proof of their safety and effectiveness. A study showed that vitamin C was able to reduce heavy bleeding in 87% of women who participated. I am now Post-Menopausal (58) and am now, after higher doses, also, Hi I have estrogen D in the process of getting better im using cream at high dose my vit d levels are great. Perimenopause occurs between the ages of 40 and 50. Hello Ive been on DIM for almost a year and had to stop. Chasteberry and DIM are the greatest vitamins for hormone imbalance. your Facebook account, or anywhere that someone would find this page valuable. You should only use natural remedies during your period if they . DIM may also inhibit DHT, a form of testosterone that is five times more potent than testosterone. Im hoping the weight gain does too. First, I suggest avoiding the foods below for just 2-4 weeks to see if there is improvement in symptoms. . Aromatase is an enzyme that assists in the conversion of testosterone to estrogen. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Video: Why You Need Zinc and Where to Find It. Mu bloodwork revealed estrogen dominance. Is Garcinia Cambogia Safe for Weight Loss? In both men and women, higher 2-hydroxy levels offer the optimal balance for testosterone response. DIM benefits include supporting a healthy menopausal transition, promoting hormonal balance in those with polycystic ovarian syndrome (PCOS). It was still very heavy but I didn't leak for the first time since I could remember. I have missed a day here and there. "The daily recommended intake of 600 IUs is debatable since studies show higher amounts of D are necessary for disease- and cancer-prevention benefits." Start by getting your levels checked to. In addition, having calcium d-glucarate available can ensure your bowels are able to effectively move the estrogen metabolites created by the liver out of the body. I didn't see much of a difference until I learned to up the dose and stop taking during my period. I stopped DIM immediately. However, some preliminary research is promising. Notably, a mouse study found that DIM helped prevent cervical cancer. With type 1 diabetes, the body does not produce any insulin. A 365-day pill also is available. Symptomatic Relief From Supplements You can take your DIM capsules with or without a meal. This is similar to many 40:1 myo- / D-chiro inositol products. Some women feel buffeted by hot flashes and wiped out by heavy periods; many have no bothersome symptoms. The most favorable of the three is 2OHE1. This is a very common condition that affects the health of women all over the world (often unknowingly). It is also important to note that 16OHE1 metabolites could also stimulate estrogen-sensitive cancer cells, which if left unchecked, could lead to breast tumors. Periods will start to become irregular, until they disappear altogether. Copy and paste it, adding a note of your own, into your blog, a Web page, forums, a blog comment, Within the liver there are two steps to estrogen metabolism known as Phase 1 and Phase 2 detox. Learn more about Balance Womens Hormone Support. DIM at 10mg/kg also lowered the number of . Lowers toxins . Reply. I take 2 a day. Researchers concluded that, in women taking tamoxifen, DIM promoted healthier estrogen metabolite production. The other metabolites, 4OHE1 and 16OHE1 are associated with unfavorable growths of breast and uterine tissue, including cancer. If we have estrogen dominance, it will work out which hormone is less and get the body to create more of the hormone we need. Where do you start if DIM stopped working for you? There is also data to support its benefits in certain cancers. I recently ran out of the DIM and noticed my night sweats went away on day 2 of not taking them. 3. Calcium d-glucarate mitigates the effect of betaglucuronidase. Sex Drive has decreased. Estrogen dominance symptoms might mimic those of perimenopause, menopause, or even PMS. Estrogen imbalance or excess estrogen, often called estrogen dominance can lead to a cascade of undesirable symptoms like hormonal headaches, breast tenderness, and PMS, to name a few. Concentration issues Irritability and moodiness. Other chronic diseases that place a strain on your body over time might also cause your period to vary. Under normal conditions, blood glucose (sugar) levels rise after you eat and then fall as liver cells produce more glucose or muscles absorb it from the blood. This can result in painful cramps, heavy periods, pain with sex, and spotting between periods. If you don't have regular periods, take it for 25 days, then stop for five days, then repeat until a regular cycle is established. Changes in Hormone Levels. If you have ovulation pain, also called mittelschmerz, you may experience twinging or cramps during ovulation. DIM may specifically boost the formation of 2-hydroxyestrone, a less strong but more favorable type of estrogen ( 1 ). What Is The Number One Food Supplement In The World? An increasing amount of people are taking DIM supplements to help with issues like acne, premenstrual syndrome (PMS), weight loss and maybe even cancer. My main reason for seeking out progesterone was to help with the heavy periods I get every month. Zeligs MA, Brownstone PK, Sharp ME, et al. By helping the body maintain a more favorable estrogen profile, DIM may help mitigate the symptoms of perimenopause and menopause when the culprit is estrogen imbalance. DIM supports liver enzymes that may help with Phase 1 estrogen metabolism, which is the phase that packages hormones and toxins up for elimination. Your doctor will conduct a complete health history and physical examination to identify possible causes for your symptoms. Due to limited research, proper dosages for DIM are unknown. Problems can arise when there is too much estrogen circulating in our bodies or the wrong metabolites. She suggested Aygestin (synthetic progesterone) to get it back in phase or an ablation. DIM supplements are neither poisonous or have major negative effects, according to current human studies. Dimming can help improve your overall mood if you're feeling down or stressed out. Can Estroblock start working that quickly in my body? However, their effectiveness for other hormone-related conditions hasnt been widely studied. tomatoes. One of those hormones is you guessed it estrogen. The dosage: As a dietary supplement for adults, take 1 Diatom Rx capsule per day (2 hours before or after meals). Certain medical issues might also have an impact on your menstruation. Consistently. My breasts hurt (which never usually happens to me) and when my period finally came it was so awful. Q: I am worried about taking DIM because I don't want it to lower my estrogen levels. There was mostly some flooding and clots at the beginning instead of all the way through and surprisingly a dramatic decrease in pain! avocados. Hello pls pass on this message to as many women as you can - heavy bleeding with fibroids - just take VIT B6 100 gms daily - if periods are heavy take VIT B6 either 50g mg and 50 mg Am and Pm - VIT B6 halts minimizes bleeding and prevents spotting - also load up on progesterone rich foods but VIT B6 is a simple over the counter that . I3C is found in cruciferous vegetables, such as: You will not get as much DIM from a vegetable as you would from a capsule. For more, check out my book Hormone Repair . Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells. getting enough sleep and keeping a regular sleep schedule. Keep in mind that human studies are needed. Current human research doesnt show DIM supplements to be toxic or have serious side effects. Am I not supposed to take it after ovulation? Supplements work gently and gradually, so they must be taken every day throughout the month not just during your period. Each of these doses contains 2000 mg of myo-inositol and 50 mg D-chiro inositol. Thanks Wray and Diane for your info and advice. After all, vegetables like broccoli and kale are rich sources of important nutrients, including fiber, antioxidants, vitamins, and minerals. Take bioidentical or body-identical progesterone (brand names Prometrium or Utrogestan) which can relieve symptoms of both estrogen excess and estrogen deficiency. Thanks. DIM supplements resulted in a significantly improved ratio of two types of estrogen 2-hydroxyestrone and 16-hydrozyestrone (8). Robinson DP, Klein SL. To understand how DIM supports your estrogen we first have to understand how estrogen is metabolized. I asked about natural progesterone and she said it wasn't strong enough. A yearlong study gave 130 women with breast cancer on tamoxifen therapy either a placebo or 150 mg of DIM twice a day. I've been taking Lugol's 2% but it makes my stomach upset to take it by mouth, so I rub it on my skin. Should I take my DIM capsules with a meal? I don't break out from being on cycle (and I've run some decently heavy cycles), although I am generally not acne prone. Avoid foods high in histamines. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. When your body no longer needs estrogen it is the livers job to package it up so it can be sent out via the urine and stool. Last medically reviewed on July 22, 2020. Estrogen dominance could unfortunately come about for various reasons: anovulation (no ovulation), stress, adrenal issues, excess fat in the body, the environment, digestive problems, and autoimmune conditions. I didn't notice much of a difference. Im 50 years old and thought maybe I was starting to go into menopause. Always talk to your doctor before adding a supplement to your diet., Denver Vein Center: DIM Supplements: What You Need to Know., Harvard Health: By the way, doctor: What does Indolplex do? Getting your vitamins and minerals through diet., Memorial Sloan Kettering Cancer Center: Diindolylmethane., Toxicology Letters: Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR.. That dose did not affect sperm growth or testicular tissue. One of the most significant things DIM may do for women is improve estrogen metabolism. Due to a lack of research in humans, little is known about the long-term safety and side effects of DIM supplements. In fact, they may be harmful to some women. The rest of the period is normal with surprise flooding now and then even on the last day. Solutions for Histamine Intolerance: #1. Researched and developed by several nutritionists, botanists, biochemists, and doctors who've approved it as an effective supplement to take during chemotherapy. Test-tube and animal studies suggest that DIM supplements may help prevent the growth and spread of breast cancer cells. I started to have extreme night sweats to the point I couldnt sleep because it was like I jumped into a pool. If after 6 months you are still enjoying benefits, you can continue taking it for a year or more. So DIM may not have much benefit. While a DIM supplement may be helpful for some women, it is not essential for everyone. It's great that it works for you and your daughter. DIM possesses hormone-modulating effects. For the first few years after menstruation begins, long cycles are common. Left unchallenged, estrogen is allowed to stimulate tissues and as it goes through its own peaks and troughs, it can trigger hot flashes, night sweats, and mood swings. 6. Made from non-GMO-certified soybeans, this product is a plant-based source of phytoestrogens to provide holistic supplementation for a . If you are thinking about taking dim, ask yourself these questions: Is dimming beneficial for me? Brighten, J.. Natural Remedies for Cramps & PMS. While subjective, on. Less common side effects included nausea, diarrhea, vomiting and a skin rash. Thanks Diane! Your menstrual cycle and period are controlled by hormones like estrogen and progesterone. Nonetheless, further studies are needed particularly for uses related to acne, weight loss, and PMS symptoms, which arent currently backed by human research. Estrogen imbalances have been linked to weight gain in both men and women, especially during menopause and andropause, when estrogen levels are most variable. It also makes you have a period if you're not pregnant. The North American Menopause Society. Perimenopause is the period between a womans later reproductive years and menopause. A Hormonal Association between Estrogen Metabolism and Proliferative Thyroid Disease. From erratic (and often, heavy) periods to weight gain, as well as hot flashes, swollen breasts and mood swingsthese symptoms are quite common during perimenopause. Fibroids, polyps, and endometrial lesions, like those seen in endometriosis, can also be stimulated by estrogen. Get regular, high-quality sleep. Other uses of DIM supplements, such as weight loss and acne treatment, have not been studied in humans. Difficulty with weight gain on your hips, butt, or thighs, Hair loss, or hair popping up where you dont want it. The when to take dim during cycle is a question that many women have. It's then excreted in the bile, but an enzyme in the intestine called beta-glucuronidase reverses the glucuronidation process. Excessive weight also puts more stress on your heart and other organs. However I also started to notice weight gain. As Ill explain in this article, DIM supports the body in producing more favorable estrogen metabolites, specifically 2-hydroxy estrogen (2OH). Let us know in the comments. For many women, this means struggling with symptoms like menstrual irregularity, moodiness, irritability, vaginal dryness, hot flashes, and night sweats for years. So, in other words, it regulates everything and lets the body determine what it needs and in what quantities. In fact, it may help combat prostatic intraepithelial neoplasia (PIN), a condition thats characterized by prostate cell growth and considered to be a precursor to prostate cancer (14). Avoid alcohol or drugs which can damage the liver and will lead to an increase in estrogen due to the lack of estrogen breakdown. The best answer I can give you is when your cycle begins, so if you dont know when your cycle has begun, then its best to ask your doctor. Intriguingly, observational studies associate high cruciferous vegetable intake with a reduced risk of certain cancers, including breast and prostate cancer. 16alpha-OHE1 is regarded as a potent oestrogen, whereas 2 . Before starting any new diet or fitness program, consult your physician to ensure you are not at risk for adverse effects or side effects from any prescribed medications. Chan EK, Sepkovic DW, Bowne HJY, Yu GP, Schantz SP. . The first period I had was very slightly better. Join in and write your own page! Hi Shifa! Uses and potential benefits of DIM supplements, Cruciferous Vegetables: Health Benefits and Recipes. DIM and other plant indoles are found in . It looked like a crime scene. 2005 - 2023 WebMD LLC. Stay hydrated: Drinking plenty of water can help lighten your flow and reduce your chances of leakage. The dosage of bioavailable, microencapsulated DIM for males participating in a physical conditioning program should be between 150 and 400 mg per day. This can result from the ovaries or other tissues producing too much estrogen, testosterone being converted into estrogen, or from poor metabolism of estrogen itself. John Staughton is a traveling writer, editor, publisher and photographer with English and Integrative Biology degrees from the University of Illinois in Champaign-Urbana (USA). However, a study in 24 healthy people found that although DIM doses of up to 200 mg were well tolerated and didn't cause side effects, one person experienced nausea, headache, and vomiting after . The eggs are super tiny too small to see with the naked eye. DIM may also cause tumor cells to self-destruct, assisting in the removal of excess estrogen from the body. During both perimenopause and menopause, hormone patterns begin to change. This is restrictive but I promise you'll see results pretty quickly and you'll know whether this might be an issue for you. I still didn't feel much of a difference pos or neg until my march period. DMPA injection (Depo-Provera) Depot medroxyprogesterone acetate (DMPA) is a type of progestin that you receive by injection every 90 days. Hopefully this will make a difference. Taking regular breaks from vitex can prevent attenuation of its effects. For instance, some studies suggest DIM encourages the death of cancer cells. All the same, studies link an imbalance of estrogen either too much or too little to an increased risk of weight gain in both men and women (16, 17, 18). Test-tube and animal studies likewise suggest that DIM helps fight prostate cancer. Put the lubricant around the tampon and try to slide it out. For people weighing over 200 lbs, take 2 Diatom Rx capsules per day. This is also why, while beginning Baseline+, it is advised that you start with 1 capsule and gradually increase every 5 days until you reach the recommended dose. In a 12-month study, 21 men with high-grade PIN were given either a placebo or 900 mg of DIM per day. PMS symptoms are worsening. If you suffer from inexplicable weight gain and struggle to lose it, mood swings, fluid retention, lumpy breasts, sugar cravings, abnormal periods, or other issues, then this may be the reason. I think taking DIM was a mistake for me. Taking DIM in high amounts can cause adverse side effects such as vomiting, headaches and nausea. Any advice? I see that you are supposed to take other supplements at certain times in your cycle, when should I take DIM? This is why DIM can possibly prevent the excess production of estrogen and support healthy testosterone levels. Cauley, J. Deficiency of Vitamin B6 and Magnesium. A fierce patient advocate and completely dedicated to uncovering the root cause of hormonal imbalances, Dr. Brighten empowers women worldwide to take control of their health and their hormones. Dr. Brighten is an international speaker, clinical educator, medical advisor within the tech community, and considered a leading authority on womens health. of natural progesterone (another brand) and cleaning out a majority of the possible hormone disrupters in my life mid November 2014. Although this web site is not intended to be prescriptive, it is intended, and hoped, that it will induce in you a sufficient level of scepticism about some health care practices to impel you to seek out medical advice thatis not captive to purely commercial interests, or blinded by academic and institutional hubris. there is not enough progesterone to oppose estrogen). DIM has been shown to promote lipolysis in studies (fat burning). While DIM can be derived from food, it would take eating a whole lot of broccoli to match what can be found in a supplement. Your menstrual cycle might be regular about the same length every month or somewhat irregular, and your period . Calcium D-glucarate is a supplemental form of glucaric acid, an important naturally occurring chemical that helps remove toxins and unneeded hormones from the body. Use daily on days 1-28 of the month and take a 3-day break before restarting on the 1st of the next month. And thats where DIM comes in. I removed many xenoestrogens and phyto estrogens from my environment hoping that would reduce my need for alot of progesterone as well as help level out my hormones. Have been stable on Synthroid until Menopause. Still, its important to remember that research is lacking on all of these effects. She is the best selling author of Beyond the Pill and Healing Your Body Naturally After Childbirth. Thats the bad news. If you are overweight, your body may create an excess of oestrogen, one of the hormones that govern the female reproductive system. "I would say about 10% of my clients who have used DIM see a change in their menstrual . Although research is ongoing, increasing the ratio of 2-hydrozyestrone to 16-hydrozyesterone may reduce breast cancer risk and cause anti-tumor effects (8). Non-GMO Soy Isoflavones 750 mg: Recommended for Hot Flashes. Women who are pregnant or nursing should avoid using DIM supplements. Sorry to be graphic but I woke up and left a trail from my bed to bathroom. Boy was I wrong! DIM supplements are purported to aid other hormone-related conditions. 6. DIM is a compound your body creates when you eat cruciferous vegetables. If you prefer a plant-based, whole food supplement option, here's a great estrogen detox product backed by good science. I shared my protocol so you don't have to do the hours of research if facing any form of surgery. When exposed to stomach acid, these enzymes form a compound called indole-3 carbinol. DIM, as mentioned before, is thought to have the same mechanism as spironolactone. Excessively high amounts of DIM may deplete sodium, an essential nutrient. Keep in mind that 16OHE1 is the type that can lead to mastalgia and may stimulate estrogen-sensitive cancer cells, like breast cancer. I stopped the DIM right after. Less common side effects include nausea, vomiting, diarrhea, and skin rash (3). In cases of microbial dysbiosis in the gut it is possible for an enzyme known as betaglucuronidase to reactivate the metabolites created in the liver and put estrogen back into circulation. The third, Hello, i 25 years old and am taking 400 mg of Progesterone since 8 months and a lot of my many symptoms improved but I also didn't have a period since. 2800 N 6th St Unit 1 PMB 953 Saint Augustine FL 32084, Get Your FREE Hormone Starter Kit with7 Day Meal Plan & Recipe Guide, which if left unchecked, could lead to breast tumors, In a randomized, placebo-controlled trial, root cause of PMS could be due to estrogen dominance, dont always need to rely on painkillers or the pill as the only treatment for these conditions, period between a womans later reproductive years and menopause. Typically, DIM supplements come in 50300mg capsules. It's important to listen to your body and be kind to yourself during your cycle - so if you're feeling a little heavier but still want a bath, the option to wear a tampon is there. After one year of DMPA injections, 50% to 75% of women report having no periods. It can also help you relax after a hard day's work by reducing your anxiety levels. The worst-case scenario is that DIM may further osteoporosis thinning bones by lowering your bodys ability to keep a healthy bone density. Learn how to identify the symptoms, what causes it, and more. Another study shows that increased levels of 16OHE1 may lead to a greater chance of thyroid proliferative disease. This information is not intended as a substitute for the advice provided by your physician or other healthcare professional. DIM has no adverse effects and few contraindications, making it a safe and uncomplicated option to aid with conception. In the morning, I take activated charcoal (using this method) to absorb any toxins released by DIM and the cleansing of the liver.I use this DIM supplement.I take one 400 mg capsule nightly and find it to be very effective. Can I try diming out for myself? All rights reserved. Dim has no known harmful effects by itself, but it may cause problems when taken in high doses or if you have any kind of intestinal obstruction. However, menstrual cycles tend to shorten and become more regular as you age. After two weeks of supplementation, the ratio of 2OHE1 (the more beneficial estrogen metabolite) to 16OHE1 (a metabolite associated with the growth of tissue) increased, which is a shift in the right direction. However, DIM supplements are available over-the-counter and online. But as you said, it is not necessary to keep it in my regiment either way. It's difficult not to pay attention to every little twinge in your body during the TWW and wonder, "Could this be a sign of early pregnancy?" I have been using progesterone cream for the last two luteal phase cycles (very irregular 50ml doses a day/every second or third days). Producing more urine helps the body to get rid of water. What is the comorbidity group of answer choices? DIM has shown to have a number of health benefits. The night sweats come about 11 days before my period and can run into when I have my period. So the goal would not be to drop estrogen as low as possible. I have a 26 day cycle which has not let up. He or she may also perform tests to determine if you have diabetes. Use 6 days and take a 1-day break every 7 days (so 4 days of "rest" each month). DIM is a compound with a myriad of potential hormonal health benefits for women. By Stephanie Garr (Certified Nutrition Consultant) DIM is a particular supplement that has been growing in popularity, especially among women, because it can help correct hormonal imbalances. She is a member of the MindBodyGreen Collective and a faculty member for the American Academy of Anti Aging Medicine. The good news is that you dont always need to rely on painkillers or the pill as the only treatment for these conditions. In a randomized, placebo-controlled trial, women prescribed tamoxifen (a treatment for hormone-receptor positive breast cancer) were either assigned 150 mg of an oral DIM supplement or a placebo for a 12-month period. So that was a plus. Balance Womens Hormone Support is a comprehensive formula designed to help support a healthy hormone balance of estrogen, progesterone and testosterone in women.
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